This website has been developed and funded by Besins Healthcare (UK) Ltd and is intended for UK Healthcare Professionals only.
Prescribing information and adverse event reporting can be found HERE
The UK’s first and only licensed progesterone treatment for preventing miscarriage in women with a history of recurrent miscarriage who present with bleeding in the first trimester.1
Support
Prescribing Prometrium for eligible women with a history of recurrent miscarriage may help support their pregnancy and increase the chances of a successful outcome.2,3
By offering this treatment, you could support both clinical care and emotional wellbeing. In addition to its therapeutic benefits, the treatment is accompanied by carefully developed online resources aimed at helping expectant parents feel more informed.
View prescribing information
Support for patients
For patients prescribed Prometrium, the patient support website delivers essential information about Prometrium in a clear, calm and empathetic way.
Once patients understand Prometrium, direction to external resources helps patients access emotional support, stories of strength, and practical advice from expert pregnancy support communities, like Tommy’s and the Miscarriage Association.
Patient website
The patient website includes:
About Prometrium – Information on how progesterone may help to reduce miscarriage risk
How to Use – Step-by-step guidance on administration, timing, and dosage
Possible side effects – Common adverse events and how to report them to the relevant health authorities
Emotional Support & Guidance – Advice on coping with anxiety, talking to loved ones, and links to support communities (e.g. Tommy’s)
FAQs – Answers to common patient concerns, including medication absorption, administration, and considerations for sexual activity
The website is designed to give your patients everything they need to fully understand why they have been prescribed Prometrium and direct them to other places where they can find support beyond what Prometrium may offer directly.
However, patients should also be encouraged to read the patient information leaflet that comes with their medicine.
Patient support card
We created a downloadable support card which you can give to your patients to ensure they have your contact details close to hand, as well as an easy way to reach the website via a QR code.
Download the patient support card using the link below.
You can request hard copies of the patient information card via your local Besins Healthcare Key Account Manager.
Adverse events should be reported. Reporting forms and information can be found at yellowcard.mhra.gov.uk/ or search for MHRA Yellow Card in the Google Play or Apple App Store. Adverse events should also be reported to Besins Healthcare (UK) Ltd, Drug Safety on 0203 862 0920 or email drugsafety@besins-healthcare.com
- Electronic Medicines Compendium (eMC) (2024). Prometrium 400mg soft vaginal capsules – Summary of Product Characteristics (SmPC). Available at: https://www.medicines.org.uk/emc/product/16016/smpc. Accessed November 2025.
- Coomarasamy A, et al. N Engl J Med 2019;380:1815-24
- Devall AJ, et al. Cochrane Database of Systematic Reviews. 2021:4 doi:10.1002/14651858.CD013792.pub2.